The Health Benefits of Matcha

Exploring the benefits of daily Matcha and Tea drinking

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Whenever we talk about the health benefits of tea we have to be careful to stay balanced in our interpretation of the data but we should not be frightened of sharing the incredible wealth of evidence out there that shows the health-giving properties of Tea - after all it is the first Chinese medicine and has been used medicinally for millennia.

IMPORTANT CORRECTIONS:

1. In this video, I conflated RR (risk reduction) with OR (odds ratio) and therefore some of the risk reduction statements should be rephrased as Odds Ratios.

2. The protection against Hepatic and Renal damage in Diabetes was actually an animal study.

CLINICAL STUDIES AND PAPERS

GENERAL

Health Benefits and Chemical Composition of Matcha Green Tea: A Review
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796401/

The science of matcha: Bioactive compounds, analytical techniques and biological properties
https://doi.org/10.1016/j.tifs.2021.10.021

Determination of catechins in matcha green tea by micellar electrokinetic chromatography
https://doi.org/10.1016/S0021-9673(03)01133-6

Matcha Tea: Analysis of Nutritional Composition, Phenolics and Antioxidant Activity
https://pubmed.ncbi.nlm.nih.gov/31832980/

Importance of Epigallocatechin and its Health Benefits
https://doi.org/10.5530/fra.2020.2.9

Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions
https://pubmed.ncbi.nlm.nih.gov/12587987/

CARDIOVASCULAR
Tea consumption and risk of cardiovascular outcomes and total mortality: a systematic review and meta-analysis of prospective observational studies
https://doi.org/10.1007/s10654-014-9960-x

Tea consumption and cardiovascular disease risk.
https://www.ncbi.nlm.nih.gov/pubmed/24172310

Black tea consumption and serum cholesterol concentration: Systematic review and meta-analysis of randomized controlled trials.
https://www.ncbi.nlm.nih.gov/pubmed/24972454

Green and black tea consumption and risk of stroke: a meta-analysis.
https://www.ncbi.nlm.nih.gov/pubmed/19228856

Green and black tea for the primary prevention of cardiovascular disease.
https://www.ncbi.nlm.nih.gov/pubmed/23780706

Tea, flavonoids and stroke in man and mouse.
https://www.ncbi.nlm.nih.gov/pubmed/20361928

Tea consumption and cardiovascular disease risk 1 – 3
http://ajcn.nutrition.org/content/early/2013/10/30/ajcn.113.059345.full.pdf

Does tea affect cardiovascular disease? A meta-analysis
https://pubmed.ncbi.nlm.nih.gov/11549554/

Association between Green Tea Consumption and Risk of Stroke in Middle-Aged and Older Korean Men: The Health Examinees (HEXA) Study
https://pdfs.semanticscholar.org/be4c/85e6d6a11b55fbb3b2f150543cb69d69320b.pdf

The Impact of Green Tea Consumption on the Prevention of Hemorrhagic Stroke
https://www.ncbi.nlm.nih.gov/pubmed/26021303

Short- and long-term black tea consumption reverses endothelial dysfunction in patients with coronary artery disease
https://pubmed.ncbi.nlm.nih.gov/11447078/

Diet and heart disease prevention
https://www.newhope.com/health-conditions/diet-and-heart-disease-prevention

Matcha and Its Components Control Angiogenic Potential
https://www.jstage.jst.go.jp/article/jnsv/67/2/67_118/_article/-char/ja/

ANTI-CANCER
Anti-tumor activity and the mechanism of a green tea (Camellia sinensis) polysaccharide on prostate cancer
https://doi.org/10.1016/j.ijbiomac.2018.10.101

Green tea and the risk of prostate cancer - A systematic review and meta-analysis
https://journals.lww.com/md-journal/Fulltext/2017/03310/Green_tea_and_the_risk_of_prostate_cancer__A.17.aspx

Protective effect of green tea against prostate cancer: A case-control study in southeast China
https://doi.org/10.1002/ijc.11550

Anti-Cancer Effects of Green Tea Polyphenols Against Prostate Cancer
https://pdfs.semanticscholar.org/9836/dd684d8402ecf08e0b55f7a82d6821c63ce9.pdf

Protective effect of green tea on the risks of chronic gastritis and stomach cancer
https://doi.org/10.1002/ijc.1231

Green tea and risk of breast cancer in Asian Americans
https://doi.org/10.1002/ijc.11259

Epigallocatechin-3-Gallate in Breast and Colon Cancer Therapy: an in Vitro and in Vivo Study
http://tesi.cab.unipd.it/63180/1/Tesi_di_Laurea_Arianna_Parma.pdf

Effect of green tea derived compounds on the growth of androgen independent prostate cancer in vivo
http://hdl.handle.net/10722/131513

From tea to treatment; epigallocatechin gallate and its potential involvement in minimizing the metabolic changes in cancer
https://doi.org/10.1016/j.nutres.2019.12.004

Green tea for ovarian cancer prevention and treatment: A systematic review of the in vitro, in vivo and epidemiological studies
https://www.gynecologiconcology-online.net/article/S0090-8258(12)00336-8/fulltext

EGCG inhibited bladder cancer SW780 cell proliferation and migration both in vitro and in vivo via down-regulation of NF-κB and MMP-9.
https://doi.org/10.1016/j.jnutbio.2016.12.004

Theaflavin-Containing Black Tea Extract: A Potential DNA Methyltransferase Inhibitor in Human Colon Cancer Cells and Ehrlich Ascites Carcinoma-Induced Solid Tumors in Mice
https://doi.org/10.1080/01635581.2020.1828943

Tea (Catechins Including (−)-Epigallocatechin-3-gallate) and Cancer
https://www.semanticscholar.org/paper/Tea-(Catechins-Including-and-Cancer-Devkota-Adhikari-Devkota/100f6e35499b29018569ef9d5219bd51ac539959

Anticancer Effects and Molecular Target of Theaflavins from Black Tea Fermentation in Vitro and in Vivo.
https://pubs.acs.org/doi/10.1021/acs.jafc.1c05313

In vitro and in vivo evaluation of silver needle white tea extract against colon cancer
https://www.researchsquare.com/article/rs-42370/v1

Pu-erh Tea Has In Vitro Anticancer Activity in TCA8113 Cells and Preventive Effects on Buccal Mucosa Cancer in U14 Cells Injected Mice In Vivo
https://doi.org/10.1080/01635581.2014.916317

Combination of resveratrol and green tea epigallocatechin gallate induces synergistic apoptosis and inhibits tumor growth in vivo in head and neck cancer models
https://pdfs.semanticscholar.org/65d6/ee5483c9227eb07fdc2618014856947673c0.pdf

The Modulating Influence of Tea Polyphenols on Estrogen Metabolism in Asian and Caucasian Populations: Breast Cancer Prevention
https://doi.org/10.1016/B978-0-12-384937-3.00046-X

Matcha green tea (MGT) inhibits the propagation of cancer stem cells (CSCs), by targeting mitochondrial metabolism, glycolysis and multiple cell signalling pathways
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128439/

Effects of green tea, matcha tea and their components epigallocatechin gallate and quercetin on MCF‑7 and MDA-MB-231 breast carcinoma cells
https://www.spandidos-publications.com/10.3892/or.2019.7430

Synergistic enhancement of anticancer effects on numerous human cancer cell lines treated with the combination of EGCG, other green tea catechins, and anticancer compounds
https://link.springer.com/article/10.1007%2Fs00432-014-1899-5

Green Tea Extracts for the Prevention of Metachronous Colorectal Adenomas: A Pilot Study
https://cebp.aacrjournals.org/content/17/11/3020

COGNITION AND NEUROPROTECTION
Theanine, the Main Amino Acid in Tea, Prevents Stress-Induced Brain Atrophy by Modifying Early Stress Responses
https://pdfs.semanticscholar.org/caaa/eb2345f74169495b70184c08e482b793aa0f.pdf

Association between tea consumption and risk of cognitive disorders: A dose-response meta-analysis of observational studies
https://pdfs.semanticscholar.org/ea79/72d6dd31b63cc8a2c64ba081f7a8ff02aa19.pdf

Effect of Green Tea Phytochemicals on Mood and Cognition
https://pubmed.ncbi.nlm.nih.gov/28056735/

Effects of Matcha Green Tea Powder on Cognitive Functions of Community-Dwelling Elderly Individuals
https://www.mdpi.com/2072-6643/12/12/3639/htm

Powdered Green Tea (Matcha) Attenuates the Cognitive Dysfunction via the Regulation of Systemic Inflammation in Chronic PM2.5-Exposed BALB/c Mice
https://www.mdpi.com/2076-3921/10/12/1932/htm

Matcha Improves Metabolic Imbalance-Induced Cognitive Dysfunction
https://www.hindawi.com/journals/omcl/2020/8882763/

An intervention study on the effect of matcha tea, in drink and snack bar formats, on mood and cognitive performance
https://doi.org/10.1016/j.foodres.2017.05.002

METABOLIC
Matcha Green Tea Drinks Enhance Fat Oxidation During Brisk Walking in Females
https://journals.humankinetics.com/view/journals/ijsnem/28/5/article-p536.xml

Effect of short-term green tee (Matcha) supplementation on fat oxidation during progressive exercise on the treadmill in obese women
https://doi.org/10.29252/JSMT.18.20.77

Can you enhance exercise-induced fat oxidation with green tea drinking?
http://eprints.chi.ac.uk/id/eprint/3965/

Three Weeks Daily Intake of Matcha Green Tea Powder Affects Substrate Oxidation during Moderate-Intensity Exercise in Females
https://doi.org/10.1080/19390211.2020.1811443

Matcha Green Tea Alleviates Non-Alcoholic Fatty Liver Disease in High-Fat Diet-Induced Obese Mice by Regulating Lipid Metabolism and Inflammatory Responses
https://www.mdpi.com/2072-6643/13/6/1950/htm

Matcha, a Powdered Green Tea, Ameliorates the Progression of Renal and Hepatic Damage in Type 2 Diabetic OLETF Rats
https://doi.org/10.1089/jmf.2008.1282

Matcha and Sencha green tea extracts with regard to their phenolics pattern and antioxidant and antidiabetic activity during in vitro digestion
https://link.springer.com/article/10.1007/s13197-021-05086-5

Matcha green tea prevents obesity-induced hypothalamic inflammation via suppressing the JAK2/STAT3 signaling pathway
https://pubs.rsc.org/en/content/articlelanding/2020/fo/d0fo01500h/unauth

The effects of the aqueous extract and residue of Matcha on the antioxidant status and lipid and glucose levels in mice fed a high-fat diet
https://pubs.rsc.org/en/content/articlehtml/2016/fo/c5fo00828j

ANTI-STRESS
Stress-reducing effect of cookies containing matcha green tea: essential ratio among theanine, arginine, caffeine and epigallocatechin gallate
https://doi.org/10.1016/j.heliyon.2019.e01653

Matcha consumption maintains attentional function following a mild acute psychological stress without affecting a feeling of fatigue: A randomized placebo-controlled study in young adults
https://doi.org/10.1016/j.nutres.2020.12.024

Stress-Reducing Function of Matcha Green Tea in Animal Experiments and Clinical Trials
https://pdfs.semanticscholar.org/ec00/d2d68f7aefa93cc939eb9e9bc723407c5ae0.pdf

Effects of Daily Matcha and Caffeine Intake on Mild Acute Psychological Stress-Related Cognitive Function in Middle-Aged and Older Adults: A Randomized Placebo-Controlled Study
https://pdfs.semanticscholar.org/9003/2db4ca3a16699f12159456951003d8c682ce.pdf

The Effects of Green Tea Amino Acid L-Theanine Consumption on the Ability to Manage Stress and Anxiety Levels: a Systematic Review
https://doi.org/10.1007/s11130-019-00771-5

Theanine, Antistress Amino Acid in Tea Leaves, Causes Hippocampal Metabolic Changes and Antidepressant Effects in Stress-Loaded Mice
https://pdfs.semanticscholar.org/d01c/3d08f3d1c146ddd2e9593fa7eef076ed80ee.pdf

Influence of continued ingestion of matcha on emotional behaviors after social stress in mice
https://doi.org/10.1080/09168451.2019.1637713

ANTI-INFLAMMATORY
Antioxidant, Anti-Inflammatory, and Antibacterial Potential of Different Drinks Based on Matcha Tea
https://doi.org/10.1088/1757-899X%2F374%2F1%2F012072

ANTI-VIRAL AND ANTI-BACTERIAL
Anti-infective potential of catechins and their derivatives against viral hepatitis
https://doi.org/10.7774/cevr.2018.7.1.37

Significant inactivation of SARS-CoV-2 by a green tea catechin, a catechin-derivative and galloylated theaflavins in vitro
https://doi.org/10.1101/2020.12.04.412098

Antiviral activity of green tea and black tea polyphenols in prophylaxis and treatment of COVID-19: A review
https://doi.org/10.1016/j.phymed.2020.153286

Can phytotherapy with polyphenols serve as a powerful approach for the prevention and therapy tool of novel coronavirus disease 2019 (COVID-19)?
https://doi.org/10.1152/ajpendo.00298.2020

Matcha Green Tea Exhibits Bactericidal Activity against Streptococcus pneumoniae and Inhibits Functional Pneumolysin
https://www.mdpi.com/2079-6382/10/12/1550/htm

DIGESTION
Changes in Intestinal Microbiota of Type 2 Diabetes in Mice in Response to Dietary Supplementation With Instant Tea or Matcha
https://doi.org/10.1016/j.jcjd.2019.04.021

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